Found 7 matching trials
Study of Efficacy and Safety of LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma
PHASE2The primary purpose of this study is to evaluate the efficacy of LXH254 com...
Status
Active Not Recruiting
Location
The Angeles Clinic and Research Institute
Phase I Study of LXH254 in Patients With Advanced Solid Tumors Haboring MAPK Pathway Alterations
PHASE1A Phase I Study of LXH254 in Patients With Advanced Solid Tumors That Harbo...
Location
Massachusetts General Hospital MGH Cancer Center
A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations
PHASE1To evaluate the efficacy of naporafenib administered with trametinib in pat...
Status
Active Not Recruiting
Location
University of California, San Francisco
Study of EGF816 in Combination With Selected Targeted Agents in EGFR-mutant NSCLC
PHASE1The study purpose is to evaluate the safety, tolerability, and preliminary ...
Status
Active Not Recruiting
Location
Novartis Investigative Site
A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)
PHASE3Stage 1: To select the optimal dose of naporafenib + trametinib to be studi...
Status
Active Not Recruiting
Location
Mayo Clinic - Arizona
A Phase Ib Study of LXH254-centric Combinations in NSCLC or Melanoma
PHASE1To characterize safety and tolerability and identify a recommended dose and...
Location
University of California San Diego .
A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer
PHASE1A phase Ib, open-label platform study of select drug combinations chosen in...
Location
University of California LA Santa Monica Location