Found 0 matching trials
Development of Novel Non-invasive Inflammometry Following Lipopolysaccharide, Endotoxin (LPS) Challenge in Healthy Volunteers
NAThe aim of this study is to further profile and develop the Lipopolysacchar...
A Clinical Study to Determine the Safety, Tolerability and Effect of RLS-0071 Doses When Given to Healthy Adults After Inhaling LPS
PHASE1This is a Phase 1b, randomized, double-blind, placebo-controlled, dose rang...
Location
Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM)
Role of TLR4 in Environmental Asthma
PHASE1The overall goal of this project is to identify genes that are involved in ...
Location
Duke University Medical Center
A Study Exploring the Use of Vaccine and Antigen Challenges for Immune Monitoring in Healthy Participants
EARLY_PHASE1The purpose of this study is to characterize the immune response in vivo us...
Location
Clinical Pharmacology Unit
Determining the Fingerprint of Endotoxin Tolerance
NAAn explorative, prospective study in 100 healthy volunteers who will be cha...
Location
Intensive Care Medicine Deparmtent
Neural Response to Inflammatory Challenge in Major Depressive Disorder
PHASE1This is a parallel group, double-blinded, placebo-controlled study. Partici...
Location
Laureate Institute for Brain Research
Lactate Metabolism After an Endotoxin Challenge in Healthy Humans
NASepsis is characterized by hyperlactatemia, the severity of which is propor...
Location
Centre Hospitalier Universitaire Vaudois
A Study of Adalimumab on Inflammatory Mediators Following a Systemic Endotoxin Challenge
PHASE1The purpose of the study is to characterize the inflammatory response to li...
Location
Clinical Pharmacology Unit
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of Inhaled GSK1995057
PHASE1GSK1995057 is a fully human, single domain antibody directed against the TN...
Location
GSK Investigational Site
Nitric Oxide, LPS and the Pathogenesis of Asthma Phase II
PHASE1The purpose of the study is to determine the role of nitric oxide (NO) in a...
Location
Duke University Medical Center