Found 40 matching trials
Study of the Effects of Itraconazole and Rifampin on LOXO-305 in Healthy Participants
PHASE1The main purpose of this study is to learn about how itraconazole and rifam...
Location
Covance Clinical Research Unit
A Study of CG-806 in Patients With Relapsed or Refractory AML or Higher-Risk MDS
PHASE1This study is being done to evaluate the safety, tolerability and antitumor...
Location
City of Hope National Medical Center
Study of Oral LOXO-338 in Patients With Advanced Blood Cancers
PHASE1The purpose of this study is to find out whether the study drug, LOXO-338, ...
Location
The University of Arizona Cancer Center
A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LOXO-305) and Digoxin (P-Glycoprotein Substrate) in Healthy Participants
PHASE1The main purpose of this study is to evaluate the effect of Pirtobrutinib (...
Location
Covance Clinical Research Unit
Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL)
PHASE3This is a study for participants with a type of blood cancer called mantle ...
Status
Active Not Recruiting
Location
Alaska Oncology and Hematology, LLC
Pirtobrutinib and Venetoclax With MRD Detection for Previously Untreated Chronic Lymphocytic Leukemia
PHASE2This phase II trial studies how well pirtobrutinib and venetoclax work in t...
Status
Active Not Recruiting
Location
Mayo Clinic in Rochester
Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Kidney Function and Healthy Participants
PHASE1The main purpose of this study is to measure how much of pirtobrutinib (LOX...
Location
Orange County Research Institute
A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib
PHASE4The master protocol study J2N-MC-JZNY provides a framework to enable the ev...
Location
Cancer Specialists, LLC
Pirtobrutinib and Venetoclax in Waldenström Macroglobulinemia
PHASE2This study is being done to examine the safety and effectiveness of pirtobr...
Status
Active Not Recruiting
Location
Beth Israel Deaconness Medical
Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma
PHASE2This phase II trial tests the safety and effectiveness of glofitamab given ...
Location
University of California, Davis