Found 29 matching trials
Study of Safety and Efficacy of LNP023 in Patients With Kidney Disease Caused by Inflammation PHASE2 Efficacy and safety of LNP023 in IgAN patients...
Location
Novartis Investigative Site
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Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Iptacopan in Pediatric Patients With Primary IgAN PHASE3 The study is an open-label, single arm, multicenter, Phase III study to det...
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Childrens Hospital Colorado
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Study on Efficacy and Safety of LNP023 in C3 Glomerulopathy Patients Transplanted and Not Transplanted PHASE2 The study is an open-label, two cohort non-randomized study evaluating the ...
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Novartis Investigative Site
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Basket Study to Assess Efficacy, Safety and PK of Iptacopan (LNP023) in Autoimmune Benign Hematological Disorders PHASE2 The main purpose of this study was to evaluate the efficacy and safety of i...
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Massachusetts General Hospital
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Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V PHASE2 The overall purpose of this two-part study is to evaluate the efficacy, saf...
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AKDHC Medical Research ServicesLLC
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Study of Efficacy and Safety of Twice Daily Oral LNP023 in Adult PNH Patients With Residual Anemia Despite Anti-C5 Antibody Treatment PHASE3 This study was a multi-center, randomized, open-label, active comparator-co...
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City Of Hope National Med Center City of Hope Medical Center
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Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN PHASE2 A study to investigate the impact of iptacopan treatment on the underlying ...
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University of Alabama at Birmingham
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Efficacy and Safety of LNP023 Compared With Rituximab in Subjects With Idiopathic Membranous Nephropathy PHASE2 This was a randomized, open-label, two arm, parallel group, proof-of-concep...
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Novartis Investigative Site
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A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy PHASE3 The purpose of this study is to evaluate the long-term safety and tolerabil...
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Active Not Recruiting
Location
AZ Kidney Dise and Hypertension Ctr
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Pharmacokinetic (PK) and Safety Study of Iptacopan (LNP023) in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Matched Control Healthy Participants With Normal Hepatic Function. PHASE1 This was an open-label, single dose parallel group study to evaluate the PK...
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Novartis Investigative Site
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