Found 12 matching trials
Trial to Evaluate Efficacy and Safety of LIB003 and Inclisiran in High-risk CVD Patients
PHASE3Comparison of LDL-C reductions of lerodalcibep (LIB003) 300 mg to inclisira...
Location
CHU de Nantes - Hôpital Nord Laennec
A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia
PHASE3This randomized study is to assess LDL-C reductions at Week 12 with monthly...
Location
Beijing Anzhen Hospital of Capital Medical University
Study of Long-Term Efficacy and Safety of LIB003 in CVD or High Risk for CVD Patients Needing Further LDL-C Reduction
PHASE3This study is to assess LDL-C reductions at Week 52 with monthly (Q4W \[≤31...
Location
Sterling Research Group
Open-Label Extension to Evaluate the Longer Term Efficacy and Safety of LIB003
PHASE2To assess the longer term safety, tolerability, and LDL C lowering efficacy...
Location
Sterling Research Group
Trial to Evaluate Efficacy and Safety of LIB003, Evolocumab and Alirocumab in High-risk CVD Patients
PHASE3Comparison of LDL-C reductions at Week 12 of monthly (Q4W\[≤ 31 days\]) dos...
Location
Sterling Research Group
Cross-Over Study to Compare the Pharmacokinetics and Pharmacodynamics of LIB003 Process 1 and Process 2 Drug Product
PHASE3To compare the pharmacokinetics (PK), and pharmacodynamics (PD) of single s...
Location
Metabolic & Atherosclerosis Research Center (MARC)
Study to Evaluate Efficacy and Safety of LIB003 in Patients on Lipid-Lowering Therapy Needing Additional LDL-C Reduction
PHASE2Study to assess the LDL-C lowering efficacy of different doses of LIB003 ad...
Location
Midwest Institute For Clinical Research
Study of Efficacy and Safety of LIB003 in Patient With CVD on Statins Requiring Additional LDL-C Reduction
PHASE3This study is to assess LDL-C reductions at Week 52 with monthly (Q4W \[≤31...
Location
Sterling Research Group
Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Further LDL-C Reduction
PHASE3The study is to assess the long-term safety, tolerability, and efficacy aft...
Status
Enrolling By Invitation
Location
NorthShore University Health System
Study to Evaluate the Safety, PK, and Pharmacodynamics of LIB003
PHASE1Randomized, double-blind, placebo-controlled, single ascending dose study i...
Location
Medpace (MARC/CPU)