Found 51 matching trials
Phase I/II Study of LDE225 With Gemcitabine and Nab-paclitaxel in Patients With Pancreatic Cancer PHASE1 The 5 year survival of patients with locally advanced or metastatic pancrea...
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Academic Medical Center
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Post-authorization Safety Study on the Long Term Safety of Sonidegib in Patients With Locally Advanced Cell Carcinoma N/A Collect real world safety data on the use of sonidegib in adult patients wi...
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Katholisches Klinikum Bochum St. Josef-Hospital
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A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome Patients PHASE2 Part I was a double-blind, randomized, vehicle-controlled Proof of Concept ...
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Novartis Investigative Site
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SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors PHASE1 Approximately 90% of children with malignant brain tumors that have recurre...
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St. Jude Children's Research Hospital
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Sonidegib and Lenalidomide After Stem Cell Transplant in Treating Patients With Multiple Myeloma PHASE2 This phase II trial studies how well sonidegib and lenalidomide after stem ...
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Blue-Light Photodynamic Therapy and Sonidegib for Multiple Basal Cell Carcinomas PHASE1 This research study is testing combination Blue-light photodynamic therapy ...
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Medical Dermatology Specialists
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LDE225 and Paclitaxel in Solid Tumors PHASE1 The primary aim of this trial is to establish the maximum tolerated dose (M...
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Istituto Oncologico della Svizzera Italiana
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LDE225 + Docetaxel/Prednisone for Adv/Met Castrate Resistant Prostate Cancer w/ Disease Progression After Docetaxel PHASE1 The purpose of this study is to first determine the highest dose of LDE225 ...
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John Theurer Cancer @ HackensackUMC
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Safety/Efficacy Study of LDE225 (Sonidegib) Plus Bortezomib in Patients With Relapsed or Relapsed/Refractory Multiple Myeloma PHASE2 The purpose of the study is to determine whether the combination of LDE225 ...
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Colorado Blood Cancer Institute
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Study of Efficacy and Safety of LDE225 in Adult Patients With Relapsed/Refractory Acute Leukemia PHASE2 The study will evaluate the efficacy, safety and tolerability of two dosing...
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Duke University Medical Center SC-5
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