Found 230 matching trials
Neprilysin Inhibition to Reduce Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction PHASE4 Cardiac magnetic resonance imaging (MRI) measures of myocardial interstitia...
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Multiple Locations
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Study of the Efficacy and Safety of LCZ696 Alone and in Combination With Amlodipine in Patients With Hypertension PHASE3 To evaluate the blood pressure lowering effect and safety of LCZ696 when gi...
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Multiple Locations
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Real World Experience in Heart Failure With Reduced Ejection Fraction (HFrEF) Patients Treated With sAc/vaL. N/A The study is a cohort observational, retrospective, non-interventional stud...
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Novartis Investigative Site
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Dapagliflozin on Hypotensive Heart Failure Patients After Sacubitril/Valsartan Therapy PHASE4 The DAPA-HF trial demonstrated that dapagliflozin was able to reduce the ri...
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Cheng Hsin General Hospital
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EntrestoTM (LCZ696) In Advanced Heart Failure (LIFE Study) PHASE4 The primary objective of the study is to determine whether, in patients wit...
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Cedars-Sinai Heart Institute
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The Role of Sacubitril/Valsartan in Post-acute Myocardial Infarction NA Sacubitril/Valsartan (SAC/VAL) is a new treatment of congestive heart failu...
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Andalusia Hospitals
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Six Months Clinical and Echocardiographic Outcome of ARNI LCZ696 Therapy in HFrEF Patients N/A To evaluate the clinical and echocardiographic outcome of LCZ696 therapy in...
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Assess Sacubitril/Allisartan and Amlodipine in Patients With Essential Hypertension Uncontrolled With Amlodipine PHASE3 The main objective of the study will be to assess the efficacy and safety o...
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Peking University First Hospital
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Multiple Dose Pharmacokinetics of LCZ696 and Its Metabolites in Subjects With Severe Renal Impairment vs. Matched Healthy Subjects With Normal Renal Function PHASE2 An open label, parallel-group study to determine multiple dose pharmacokine...
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Novartis Investigative Site
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Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCC PHASE4 The purpose of this study was to evaluate the effect of sacubitril/valsarta...
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Novartis Investigative Site
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