Found 10 matching trials
LCL161 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis
PHASE2This phase II trial studies how well second mitochondrial-derived activator...
Location
M D Anderson Cancer Center
A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat
PHASE1The purpose of this study was to combine the PDR001 checkpoint inhibitor wi...
Location
UCLA Santa Monica Hematology / Oncology SC
Safety and Efficacy of LCL161 in Patients With Solid Tumors
PHASE1The study will evaluate the safety of increasing doses of oral LCL161 in pa...
Location
UNC/ Lineberger Comprehensive Cancer Center Dept. of LinbergerCancerCtr(2)
A Randomized, Phase 2, Neoadjuvant Study of Weekly Paclitaxel With or Without LCL161 in Patients With Triple Negative Breast Cancer
PHASE2To assess whether adding LCL161 to weekly paclitaxel enhances the efficacy ...
Location
Highlands Oncology Group Dept of Highlands Oncology Grp
LCL161 Plus Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignancies
PHASE1This trial will investigate the combination of two anti-cancer agents to tr...
Location
Florida Cancer Specialists-Sarasota
A Study of LCL161 in Combination With Weekly Paclitaxel in Adult Patients With Advanced Solid Tumors
PHASE1This is a dose escalation study that will assess the safety and efficacy of...
Location
Dana Farber Cancer Institute SC
Safety and Tolerability of Oral LCL161 in Japanese Adult Patients With Advanced Solid Tumors
PHASE1This study will evaluate safety and tolerability to estimate the maximum to...
Location
Novartis Investigative Site
Phase I Trial of LCL161 and Gemcitabine Plus Nab-Paclitaxel in Metastatic Pancreatic Cancer
PHASE1The goal of this study is to identify the maximum tolerated dose and dose-l...
SMAC Mimetic LCL161 Alone or With Cyclophosphamide in Treating Patients With Relapsed or Refractory Multiple Myeloma
PHASE2This phase II trial studies how well second mitochondrial-derived activator...
Location
Mayo Clinic in Arizona
Study of Single Agent CJM112, and PDR001 in Combination With LCL161 or CJM112 in Patients With Multiple Myeloma
PHASE1The purpose of this study is to assess the safety, tolerability, and identi...
Location
Mayo Clinic Arizona