Found 0 matching trials
Long Term Nitric Oxide Bioavailability on Vascular Health in Chronic Obstructive Pulmonary Disease
PHASE2Chronic obstructive pulmonary disease (COPD) affects up to 14 million peopl...
Location
Georgia Prevention Institute
Study to Evaluate the Effects of Kuvan on Individuals With Phenylketonuria (PKU) With Maladaptive Behaviors
N/ATo validate the outcome measures and the tolerability of Kuvan treatment in...
Location
LAC+USC Medical Center
Open-Label Extension Study of Kuvan for Autism
PHASE2This is an open-label extension study available only to subjects who comple...
Location
The Children's Health Council
6R-BH4 Pulmonary Arterial Hypertension Study
PHASE1The purpose of this study is to determine whether the addition of sapropter...
Location
Vanderbilt Medical Center
Association Between Coronary Flow Reserve and BH4 Levels in High CV Risk
N/ATo determine if there is a relationship between coronary flow reserve (CFR)...
Location
ASST Papa Giovanni XXIII
Rhode Island Diastolic Dysfunction - Heart Failure
NATo study the hypothesis that treating patients with underlying diastolic dy...
The Effects of Sapropterin Dihydrochloride Supplementation on in Vivo Redox Status in Patients With Classical PKU
N/AThis study is an independent sub-study of the protocol titled PKU-016: A do...
Location
Multiple Locations
Oral 6R-BH4 for the Treatment of Isolated Systolic Hypertension and Endothelial Dysfunction
PHASE2This study is designed to assess the safety and efficacy of twice-daily ora...
Location
Johns Hopkins University
Impact Of A Phe-Restricted Diet On Gut Health In Children With PKU
N/APhenylketonuria (PKU) is an inherited disorder of phenylalanine (Phe) metab...
Location
Birmingham Children's Hospital
Fluorodeoxyglucose Positron Emission Tomography (FDG PET) Findings in Patients With Phenylketonuria Before and After KUVAN Therapy
NAThe aim of this pilot study is to determine if there are any changes in bra...
Location
Children's Hospital of Philadelphia, Section of Metabolism,PKU program