Found 95 matching trials
Evaluation of BH4 Responsiveness in Our PKU Patients
PHASE1This study aims to evaluate BH4 responsiveness in our PKU patients and to c...
Status
Active Not Recruiting
Location
Sohag Faculty of Medicine
Novel Approaches for Improving Vascular Function in Veterans With HFpEF
PHASE1This project will evaluate the impact of L-Citrulline, tetrahydrobiopterin ...
Location
VA Salt Lake City Health Care System, Salt Lake City, UT
Sapropterin in Individuals With Phenylketonuria
N/AInvestigators at Washington University will examine the effects of sapropte...
Location
Washington University
Nutritional Status in Phenylketonuria
N/AIn the era of Phenylketonuria (PKU) newborn screening, early diagnosis in t...
Location
Centro Hospitalar Universitário do Porto
: Vascular Function in Health and Disease
PHASE1Many control mechanisms exist which successfully match the supply of blood ...
Location
George E Wahlen VA Medical Center
Treatments Being Tested
Maximum Exercise TestsBH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-AscorbateBQ-123Fexofenadine, RanitidineAngiotensin-II, ValsartanAcetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, PhentolamineBQ-123, MitoQ, BH4 The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication
PHASE1This study will focus on people with claudication from peripheral arterial ...
Status
Active Not Recruiting
Location
UMASS Memorial Healthcare - University Campus
Study to Evaluate the Safety and Efficacy of Phenoptin™ in Subjects With Phenylketonuria Who Have Elevated Phenylalanine Levels
PHASE3The primary objective of this study is to evaluate the efficacy of Phenopti...
Location
Multiple Locations
PKU Skin Stripping
N/APURPOSE OF STUDY: To determine if a non-invasive skin stripping technique c...
Location
Cincinnati Children's Hospital Medical Center
A Study of the Effects of 6R-BH4 on Blood Pressure in Subjects With Poorly Controlled Systemic Hypertension
PHASE2The purpose of this study is to determine whether 6R-BH4 (sapropterin dihyd...
Location
Multiple Locations
Impact of KUVAN® on Gastric Relaxation in Women With Diabetic Gastroparesis.
NAKuvan® (sapropterin dihydrochloride) for Improving Gastric Accommodation in...
Location
Stanford University School of Medicine