Found 19 matching trials
KRT-232 and TKI Study in Chronic Myeloid Leukemia
PHASE1This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2...
Location
University of Alabama Birmingham
Study of KRT-232 or TL-895 in Janus Associated Kinase Inhibitor Treatment-Naïve Myelofibrosis
PHASE2This study evaluates either KRT-232 or TL-895 in treatment naïve patients w...
Location
Innovative Clinical Research Institute
Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL
PHASE1This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2...
Location
Goshen Center for Cancer Care
KRT-232 Compared to Ruxolitinib in Patients With Phlebotomy-Dependent Polycythemia Vera
PHASE2This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2...
Status
Active Not Recruiting
Location
The Kirklin Clinic of UAB Hospital
Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer
PHASE2This study evaluates navtemadlin as maintenance treatment for patients with...
Location
Kaiser Permanente Center
Study of Navtemadlin Plus Pembrolizumab as Maintenance Therapy in Locally Advanced and Metastatic Non-Small Cell Lung Cancer
PHASE1This study evaluates Navtemadlin (KRT-232) in combination with Pembrolizuma...
Location
Multiple Locations
Testing a New Chemotherapy Drug, KRT-232 (AMG-232) in Combination With Decitabine and Venetoclax in Patients With Acute Myeloid Leukemia
PHASE1This phase Ib trial studies the side effects and best dose of navtemadlin w...
Status
Active Not Recruiting
Location
City of Hope Comprehensive Cancer Center
KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment
PHASE2This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2...
Location
The Kirklin Clinic of UAB Hospital
Navtemadlin (KRT-232) With or Without Anti-PD-1/Anti-PD-L1 for the Treatment of Patients With Merkel Cell Carcinoma
PHASE1This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2...
Location
University of Colorado Anschutz Medical Campus
KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancer
PHASE2This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2...
Location
Florida Cancer Specialists - 3840 Broadway