Found 10 matching trials
Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia PHASE1 Background:
Sickle cell disease (SCD) is an inherited disorder of the bloo...
Show More Status
Active Not Recruiting
Location
National Institutes of Health Clinical Center
Learn More & Join Trial
JSP191 Antibody Targeting Conditioning in SCID Patients PHASE1 A Phase 1/2 study to evaluate the safety, tolerability, and efficacy of an ...
Show More Location
UCLA Mattel Children's Hospital
Learn More & Join Trial
A Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients With Chronic Inducible Urticaria (CIndU) Who Remain Symptomatic Despite Treatment With H1- Antihistamines PHASE1 This is an open-label, single ascending dose Phase 1b/2a trial to determine...
Show More Location
Charité - University Clinic Berlin
Learn More & Join Trial
Depleted Donor Stem Cell Transplant in Children and Adults With Fanconi Anemia After Being Conditioned With a Regimen Containing Briquilimab PHASE1 The objective of this clinical trial is to develop a cell therapy for Fanco...
Show More Location
Stanford University
Learn More & Join Trial
JSP191 (briquilimab) in Subjects with LR-MDS PHASE1 A Phase 1 study in subjects with LR-MDS to assess the safety and tolerabili...
Show More Location
Memorial Healthcare System
Learn More & Join Trial
Dose Escalation Trial Of Safety, Pharmacokinetic/Pharmacodynamic And Preliminary Clinical Activity of Briquilimab In Adult Patients With Chronic Spontaneous Urticaria (CSU) PHASE1 This trial will be performed as a three-part dose escalating clinical trial...
Show More Learn More & Join Trial
Allogeneic Hematopoietic Stem Cell Transplantation With Briquilimab-Based Conditioning in Participants With GATA2 Deficiency PHASE2 Background:
People with GATA-binding factor 2 (GATA2) deficiency have a mu...
Show More Status
Active Not Recruiting
Location
National Institutes of Health Clinical Center
Learn More & Join Trial
A Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Safety and Efficacy of Briquilimab in Participants With Allergic Asthma PHASE1 Study JSP-CP-012 is designed as a proof of concept, parallel-group, single ...
Show More Location
University of Calgary
Learn More & Join Trial
JSP191 Antibody Conditioning Regimen in MDS/AML Subjects Undergoing Allogenic Hematopoietic Stem Cell Transplantation PHASE1 This is a Phase 1a/b study to evaluate the safety and tolerability of an an...
Show More Location
City of Hope Comprehensive Cancer Center
Learn More & Join Trial
Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD) EARLY_PHASE1 Background:
Chronic granulomatous disease (CGD) is a rare immune disorder ...
Show More Status
Active Not Recruiting
Location
National Institutes of Health Clinical Center
Learn More & Join Trial