Found 18 matching trials
A Long-term Extension Study of PCI-32765 (Ibrutinib) PHASE3 The purpose of this study is to collect long-term safety and efficacy data ...
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City of Hope Cancer Center
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Combination of PCI-32765 With Obinutuzumab in Untreated Follicular Lymphoma PHASE2 Primary Objectives The primary objective of this study is to evaluate the e...
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Klinikum der Universität München
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A Pharmacokinetic Study in Healthy Participants to Assess the Pharmacokinetics and Safety of a Supratherapeutic Dose of PCI-32765 (Ibrutinib) Capsule and Solution Formulations Administered With Food PHASE1 The purpose of this study is to examine the exposure and safety of a suprat...
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Multiple Locations
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A Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Steroid Dependent/Refractory Chronic Graft Versus Host Disease (cGVHD) PHASE3 The purpose of this study is to evaluate efficacy of ibrutinib in Japanese ...
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Anjo Kosei Hospital
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Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Relapsed or Refractory Mantle Cell Lymphoma PHASE2 The purpose of this study is to evaluate overall response rate (ORR) (compl...
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Multiple Locations
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A Safety and Efficacy Study of Ibrutinib in Pediatric and Young Adult Participants With Relapsed or Refractory Mature B-cell Non-Hodgkin Lymphoma PHASE3 The purpose of this study is to confirm that the pharmacokinetics of ibruti...
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Multiple Locations
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A Study of Ibrutinib With Rituximab in Relapsed or Refractory Mantle Cell Lymphoma PHASE2 The purpose of this study is to provide continued access to treatment for p...
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Santa Casa de Misericordia de Belo Horizonte
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Proof-of-concept Study of Ibrutinib in c-MYC and HER2 Amplified Oesophagogastric Carcinoma PHASE2 Some cancers of the oesophagus and stomach express excessive copies of eith...
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The Royal Marsden NHS Trust
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A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring PHASE1 The purpose of this study is to collect long-term safety data in participan...
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Enrolling By Invitation
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Macquarie University Hospital
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A Study of the MALT1 Inhibitor JNJ-67856633 and Ibrutinib in Combination in B-cell NHL and CLL PHASE1 The purpose of this study is to determine the safety and recommended Phase ...
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