Found 10 matching trials
A Study to Investigate the Absorption, Metabolism, and Excretion of JNJ-38518168 After a Single Oral Dose in Healthy Male Participants. PHASE1 The purpose of the study is to investigate the absorption, metabolism, and ...
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A Dose Range Finding Study of JNJ-38518168 in Patients With Active Rheumatoid Arthritis in Spite of Treatment With Methotrexate PHASE2 The purpose of this dose range finding study is to assess the effectiveness...
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A Study to Evaluate Safety and Efficacy of Toreforant (JNJ-38518168) in Participants With Moderate to Severe Plaque-type Psoriasis PHASE2 The purpose of this study is to evaluate the efficacy, safety and tolerabil...
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A Study of the Safety and Pharmacokinetics of JNJ-38518168 in Japanese and Caucasian Male Participants and the Effect of JNJ-38518168 on the Blood Levels of Midazolam PHASE1 The purpose of Part 1 of this study is to evaluate the safety, tolerability...
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A Study to Evaluate the Pharmacokinetics of JNJ-38518168 in Patients With Mild and Moderate Hepatic Impairment Compared With Patients With Normal Hepatic Function PHASE1 The purpose of this study is to characterize the pharmacokinetics (what the...
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A Synovial Biopsy Study of JNJ-38518168 in Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy PHASE2 The purpose of this study is to assess the impact of JNJ-38518168 on rheuma...
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A Study of JNJ-38518168 in Symptomatic Adult Participants With Uncontrolled, Persistent Asthma PHASE2 The purpose of this study is to evaluate the efficacy, safety, tolerability...
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A Study to Investigate How JNJ-38518168 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis Participants PHASE1 The purpose of this study is to evaluate the effects of JNJ-38518168 on the...
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Effect of Ketoconazole on the Pharmacokinetics of JNJ-38518168 in Healthy Volunteers PHASE1 The purpose of this study is to evaluate the effects of repeated twice-dail...
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An Efficacy and Safety Study of JNJ-38518168 in Adult Participants With Rheumatoid Arthritis PHASE2 The purpose of this study is to evaluate the efficacy, tolerability and saf...
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