Found 13 matching trials
Glecirasib Combined With Ivonescimab for First-line Treatment of KRAS G12C-mutated NSCLC
PHASE1This study evaluates the safety, tolerability, maximum tolerated dose (MTD)...
Location
Multiple Locations
A Study of JAB-21822 in Adult Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation in China
PHASE1To assess safety, tolerability, PK, efficacy and determine recommended phas...
Status
Active Not Recruiting
Location
Beijing Cancer Hospital
A Food Effect Study of JAB-21822 in Healthy Subjects
PHASE1The primary objective of this study is to determine the effect of food in h...
Location
Beijing GoBroad Boren Hospital
JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C Mutation
PHASE1This study is to evaluate the safety, tolerability, pharmacokinetics and an...
Status
Active Not Recruiting
Mass Balance Study of [14C]JAB-21822
PHASE1Mass Balance Study of \[14C\]JAB-21822 in China Healthy Subjects...
Location
The First Affiliated Hospital of Soochow University
Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation
PHASE1This is a multicenter, open-label phase 1/2a study consisting of two parts:...
Location
The First Affiliated Hospital of USTC Anhui Provincial Hospital
A Study of JAB-21822 in Advanced or Metastatic NSCLC With KRAS p.G12C and STK11 Co-mutation and Wild-type KEAP1
PHASE1Evaluate the safety and tolerability, drug levels, and clinical activity of...
JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation
PHASE3This Phase 3 study will evaluate the efficacy of JAB-21822+JAB-3312 versus ...
Location
Anhui Province cancer hospital
A Phase II Study Evaluating JAB-21822 Monotherapy in Adult Patients With Pancreatic Cancer and Other Solid Tumors Harboring the KRAS p.G12C Mutation.
PHASE2Patients with other advanced solid tumors (excluding NSCLC and CRC) who hav...
Location
Anhui Provincial Cancer Hospital
A Clinical Trial to Evaluate JAB-21822 Drug-drug Interactions in Healthy Subjects
PHASE1This is a phase I study to evaluate drug-drug interactions (DDIs) of JAB-21...
Location
Beijing GoBroad Hospital