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Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D) PHASE1 Tegoprubart (AT-1501) is a monoclonal antibody. Antibodies are Y-shaped pro...
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Active Not Recruiting
Location
University of Chicago
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Safety and Efficacy Study of Islets Xenotransplantation NA The neonatal pig islets will be used as donor culturing with our modified c...
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Cell Transplantation and Gene Therapy Institute
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Effect of Islet Autotransplantation Compared to Oral Antidiabetic Drug. NA * Effects of autologous islet transplantation were compared to those of ora...
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Seoul National University Hospital
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Screening of Subjects With Type I Diabetes to Determine Eligibility for Islet Transplantation N/A Protocol to screen potential subjects for islet transplantation...
Location
Diabetes Research Institute
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Islet Transplantation With Recipient T-Reg Cells or Deceased Donor Vertebral Bone Marrow Therapy PHASE1 The goal of this clinical trial is to learn if patients who have brittle ty...
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Enrolling By Invitation
Location
Stanford University
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Pancreatic Islet Transplantation Into the Anterior Chamber of the Eye PHASE1 The intervention in this trial is intraocular islet transplantation. A sing...
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Bascom Palmer Eye Institute
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Beta-Cell Transplantation in Pre-Uremic Patients With Type 1 Diabetes PHASE1 To examine whether temporary immunosuppression with ATG, tacrolimus and MMF...
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Universitair Ziekenhuis and Diabetes Research Center - Brussels Free University-VUB
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Islet Cell Transplantation Alone in Patients With Type 1 Diabetes Mellitus: Steroid-Free Immunosuppression PHASE2 SPECIFIC AIMS:
1. To reverse hyperglycemia and insulin dependency in patie...
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University of Miami, Diabetes Research Institute
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Cadaveric Islet Transplantation in Patients With Insulin-Dependent Diabetes Mellitus PHASE1 We hypothesize that the following improvements to islet transplantation wil...
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The Nebraska Medical Center
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A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus PHASE1 This study is First In Human study for Encapsulated Porcine Islet Cells for...
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University of Illinois Hospital & Health Sciences System
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