Found 5 matching trials
PolyImmune {Durvalumab (MEDI4736) and Tremelimumab} & Vaccine Orchestrated Treatment for Patients With Advanced/Metastatic Renal Cell Carcinoma
PHASE2Reported in the 2018 NEJM (378; 1277) article, the combination of checkpoin...
Location
Multiple Locations
Personalized Neoantigen Vaccine in Combination With Durvalumab (MEDI4736) in Extensive Stage Small Cell Lung Cancer
PHASE2The investigators hypothesize that a personalized neoantigen vaccine combin...
Status
Active Not Recruiting
Location
Washington University School of Medicine
Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma
PHASE1This is a single institution, open-label, multi-arm, phase I study assessin...
Status
Active Not Recruiting
Location
Washington University School of Medicine
Expanded Access Neoantigen Vaccine in Solid Tumors
N/AThis is an expanded access use study. Safety data will be collected from pa...
Status
No Longer Available
Location
Washington University School of Medicine
Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors
PHASE1The purpose of this research study is to learn about the safety and feasibi...
Location
Washington University School of Medicine