Found 9 matching trials
24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients PHASE2 Transthyretin is a protein produced in the liver that transports thyroid ho...
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Brigham and Women's Hospital
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Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis N/A This study measures circulating, misfolded ATTR oligomers in asymptomatic A...
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ATTR Expanded Access Program (EAP) by Ionis N/A The purpose of this program is to provide expanded access to Inotersen for ...
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Approved For Marketing
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Multiple Locations
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TEGSEDI Pregnancy Surveillance Program N/A This is a worldwide safety surveillance study of pregnancy outcomes in wome...
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Multiple Locations
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Extension Study Assessing Long Term Safety and Efficacy of IONIS-TTR Rx in Familial Amyloid Polyneuropathy (FAP) PHASE3 This study evaluates the safety and tolerability of extended dosing with IO...
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University of California, Irvine
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Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy PHASE2 The purpose of this study is to evaluate the efficacy and safety of inoters...
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University of California, Irvine
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NEURO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy PHASE3 The main objective of this study was to evaluate the efficacy of eplonterse...
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Mayo Clinic - Arizona
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A Study to Characterize Adverse Events Occurring Within One Day of TEGSEDI Administration to Adult Participants With hATTR-PN PHASE4 The objective of the study was to characterize adverse events (AEs) occurri...
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ION-682884 in Patients With TTR Amyloid Cardiomyopathy PHASE2 Transthyretin is a protein produced in the liver that transports thyroid ho...
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Brigham and Women's Hospital
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