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Trial Search

Current Search Criteria:

Intervention: Inavolisib

Found 35 matching trials

A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer

PHASE2

This study will evaluate the safety and efficacy of inavolisib combination ...

Status

Recruiting

Location

Los Angeles Cancer Network

Start Date

2025-09-09

Trial ID

NCT07054190

Treatments Being Tested

Inavolisib Ribociclib Letrozole

A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

PHASE2

A study to evaluate the efficacy and safety of triplet combination of inavo...

Status

Recruiting

Location

Los Angeles Cancer Network - Anaheim

Start Date

2026-04-07

Trial ID

NCT07405801

Treatments Being Tested

Inavolisib Ribociclib Fulvestrant Placebo

To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer

PHASE1

This is an open-label, multicenter, Phase I study designed to evaluate the ...

Status

Active Not Recruiting

Location

Massachusetts General Hospital.

Start Date

2016-12-13

Trial ID

NCT03006172

Treatments Being Tested

Inavolisib Fulvestrant Letrozole Palbociclib Metformin Trastuzumab Pertuzumab

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

PHASE3

This study will evaluate the efficacy and safety of the combination of inav...

Status

Recruiting

Location

City of Hope - Phoenix

Start Date

2025-04-09

Trial ID

NCT06790693

Treatments Being Tested

Inavolisib Placebo CDK4/6i Letrozole

A Phase II, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Neoadjuvant Therapy With Inavolisib Plus Pertuzumab and Trastuzumab as Subcutaneous (PH-FDC SC) and 3-week Cycle Nab-paclitaxel for PIK3CA-mutated, HER2+, eBC

PHASE2

The study consists of a screening period of 28 days, a treatment period. Lo...

Status

Not Yet Recruiting

Location

Multiple Locations

Start Date

2025-12-15

Trial ID

NCT07245797

Treatments Being Tested

fixed-dose combination of pertuzumab and trastuzumab as subcutaneousformulation q3w and nab-paclitaxel in 3-week cycle for total 6 cycles with inavolisib (6 cycles) or without inavolisib.

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

PHASE1

This is a Phase IB/II multi-cohort study designed to evaluate the efficacy ...

Status

Recruiting

Location

City of Hope Comprehensive Cancer Center

Start Date

2021-10-20

Trial ID

NCT04486352

Treatments Being Tested

Atezolizumab - 28 Day Cycle Bevacizumab Ipatasertib Talazoparib Trastuzumab emtansine Tiragolumab Atezolizumab - 21 Day Cycle Inavolisib Letrozole Giredestrant Abemaciclib

A Study to Evaluate the Effectiveness and Safety of Inavolisib in Participants With Endocrine-resistant, PIK3CA-mutated, Hormone Receptor-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer

N/A

The main purpose of this study is to evaluate the effectiveness of inavolis...

Status

Recruiting

Location

The First Affiliated Hospital of Xiamen University

Start Date

2026-01-21

Trial ID

NCT07347600

Treatments Being Tested

Inavolisib Palbociclib Fulvestrant

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

PHASE3

This study will evaluate the efficacy and safety of inavolisib in combinati...

Status

Recruiting

Location

Banner Health MD Anderson AZ

Start Date

2023-09-08

Trial ID

NCT05894239

Treatments Being Tested

Inavolisib Phesgo Placebo Taxane-based Chemotherapy Optional Endocrine Therapy of Investigator's Choice

A PoC Study to Evaluate Treatments' Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population

PHASE2

This trial is a multicenter, open-label, non-comparative, phase II, biomark...

Status

Recruiting

Location

Complejo Hospitalario Universitario A Coruña (CHUAC)

Start Date

2024-04-01

Trial ID

NCT05708235

Treatments Being Tested

Giredestrant Abemaciclib Inavolisib Standard ET followed by change in treatment

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

PHASE1

Study STX-478-101 (LY4064809) is a multipart, open-label, phase 1/2 study e...

Status

Recruiting

Location

Ellison Clinic at Saint John's

Start Date

2023-04-17

Trial ID

NCT05768139

Treatments Being Tested

STX-478 Fulvestrant Ribociclib Palbociclib Letrozole Anastrozole Exemestane Tamoxifen Abemaciclib Imlunestrant Metformin

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