Found 7 matching trials
A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy Volunteers PHASE1 The primary objective of the study is to evaluate the effect of itraconazol...
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A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Praliciguat in Healthy Male Volunteers PHASE1 The primary objective is to characterize the pharmacokinetics (PK) of prali...
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Covance Clinical Research Unit Inc.
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A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF) PHASE2 The objective of the CAPACITY-HFpEF study is to evaluate the safety and eff...
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Arizona Arrhythmia Research Center
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A Phase 2 Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Stable Type 2 Diabetes and Hypertension PHASE2 To evaluate the impact of escalating doses of IW-1973 on endothelial functi...
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ICON Early Phase Unit
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Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC) in Patients With Stable Type 2 Diabetes and Hypertension PHASE2 To compare the safety, tolerability, pharmacokinetic (PK) profile, and phar...
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Trial of IW-1973 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers PHASE1 Stage 1: To assess the safety, tolerability, pharmacokinetic (PK) profile, ...
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Ironwood Investigator
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A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by Albuminuria PHASE2 To evaluate the safety and efficacy of IW-1973 in patients with type 2 diab...
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University of Alabama at Birmingham
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