Found 6 matching trials
Trial of IW-1701 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers PHASE1 The objectives of the study are to assess the safety and tolerability of a ...
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Ironwood Investigational Site
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A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat (IW-1701), in Healthy Volunteers PHASE1 To evaluate the effect of itraconazole (a potent cytochrome P450 isoenzyme ...
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A Trial of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Healthy Subjects PHASE1 The objectives of this study are:
Stage 1: To assess the safety, tolerabil...
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ICON Early Phase Unit
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Study of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Type I or II Achalasia PHASE2 The objectives of this study are as follows:
In participants with primary ...
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Connecticut Clinical Research Foundation, Gastroenterology Institute
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A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD) PHASE2 The primary objective of the 1701-202 STRONG SCD study is to evaluate the s...
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Children's Hospital of Orange County
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A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Olinciguat in Healthy Male Volunteers PHASE1 The primary objective is to characterize the pharmacokinetics (PK) of olinc...
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Covance Clinical Research Unit Inc.
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