Found 24 matching trials
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02) PHASE3 The purpose of this study is to measure the efficacy and safety of rilvegos...
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Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03) PHASE2 DESTINY-Gastric03 will investigate the safety, tolerability, pharmacokineti...
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Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC PHASE1 DESTINY-Lung03 will investigate the safety and tolerability of trastuzumab ...
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A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy PHASE1 The purpose of this study is to determine the subcutaneous (SC) dose that g...
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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer PHASE2 The purpose of this study is to further advance the ability to practice per...
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University of Alabama at Birmingham
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DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer PHASE3 DESTINY-Endometrial01 will investigate the efficacy of first-line T-DXd + r...
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A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma PHASE2 GEMINI-PeriOp GC study will assess the safety, tolerability, pharmacokineti...
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Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma PHASE3 This is a Phase III, randomised, open-label, sponsor-blinded, 3-arm, multic...
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An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC PHASE3 Purpose: to assess efficacy and safety of Dato-DXd + rilvegostomig as adjuv...
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Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01) PHASE3 A global study to assess the efficacy and tolerability of rilvegostomig com...
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Active Not Recruiting
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