Found 7 matching trials
Study of HS-10241 in Combination With Almonertinib in Patients With Locally Advanced or Metastatic NSCLC PHASE1 This study is conducted to determine the safety, tolerability, pharmacokine...
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Shanghai Chest Hospital
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A Study of HS-10241 Combined With Almonertinib Versus Platinum-based Chemotherapy in Treatment of Advanced NSCLC With MET Amplification After Failure of EGFR-TKI Therapy PHASE3 HS-10241, an oral and highly selective MET-TKI, may contribute to overcomin...
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Multiple Locations
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A Trial of C-met Kinase Inhibitor HS-10241 in Subjects With Advanced Solid Tumours PHASE1 To investigate safety, tolerability and pharmacokinetics of C-met Kinase In...
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Cancer Hospital Chinese Academy of Medical Sciences
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Pharmacokinetic Study of HS-10241 Tablets in Subjects with Hepatic Impairment and Normal Hepatic Function PHASE1 This study will be conducted in subjects with moderate Hepatic Impairment, ...
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Multiple Locations
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PhaseⅠStudy of the HS-10241 in Patients With Advanced Solid Tumors PHASE1 HS-10241 is a highly potent and selective small molecule inhibitor of c-Met...
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Shanghai Chest Hospital
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A Phase I Trial of HS-10241 in Solid Tumors PHASE1 This is a phase 1, open-label, dose-escalation trial of HS-10241 as monothe...
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Chris O'Brien Lifehouse
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Tolerability, Safety, Pharmacokinetics and Efficacy of HS-10241 Single Agent or Combined With Apatinib in Patients With Advanced Solid Tumors PHASE1 To investigate tolerability, safety, pharmacokinetics and efficacy of C-met...
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West China Hospital, Sichuan University
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