Found 8 matching trials
HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma
PHASE2The goal of this clinical trial is to evaluate in patients with advanced in...
Location
Chinese PLA General Hospital
A Study of HMPL-453 in Patients With Advanced Solid Malignancies
PHASE1This is a dose escalation study consisting of two stages: Dose-escalation s...
Location
Beijing 307 Hospital
Study on [14C]HMPL-453(FGFR Inhibitor) in Healthy Chinese Adult Male Subjects
PHASE1To evaluate the absorption, metabolism and excretion in healthy Chinese mal...
Location
The First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital)
The Study on Effects of CYP3A and P-glycoprotein Inhibitor Itraconazole and CYP Enzyme Inducer Rifampin of HMPL-453 Tartrate Tablets
PHASE1Primary objective:
1. To evaluate the effect of Itraconazole ( CYP3A and P...
Location
yijishan Hospital
HMPL-453 in Advanced Malignant Mesothelioma
PHASE2This is a phase II, single arm, multicenter and open-label study to evaluat...
Location
Shanghai Chest Hospital
A Phase Ib/II Clinical Study Evaluating HMPL-453 Tartrate as Monotherapy and in Combination With Chemotherapy or Toripalimab in Advanced Solid Tumors
PHASE1A Phase Ib/II Clinical Study Evaluating HMPL-453 Tartrate as Monotherapy an...
Location
Chinese PLA General Hospital
A Dose Escalation Study to Assess the Safety and Tolerability of HMPL-453 in Patients With Advanced Solid Malignancies
PHASE1This is a first-time-in-human, phase I, open-label, dose-escalation study o...
Location
St Vincent's Cancer Services
HMPL-453 Food Effect and PPI Study in Healthy Volunteer Study
PHASE1A Phase 1, Open-label, 4-Period, Randomized 6-Sequence Study to Evaluate th...
Location
Shanghai Xuhui Central Hospital