Found 10 matching trials
A Study of Poziotinib in Previously Treated Participants With Locally Advanced or Metastatic NSCLC Harboring HER2 Exon 20 Mutations PHASE3 The primary purpose of this study is to compare the progression-free surviv...
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Bond Clinic, P.A.
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Clinical Trial to Determine the MTD of HM781-36B in Patients With Advanced Solid Tumors PHASE1 The main objective of this study is to determine the maximum tolerated dose...
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Seoul National University Hospital
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Poziotinib in Patients With NSCLC Having EGFR or HER2 Exon 20 Insertion Mutation PHASE2 This is a Phase 2, open-label, multicenter study to evaluate the efficacy a...
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Beijing Cancer Hospital
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A Study of Poziotinib in Combination With T-DM1 in HER2-Positive Breast Cancer PHASE1 This is a Phase 1b, open-label, multicenter study to determine the Maximum ...
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Pacific Cancer Medical Center, Inc.
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A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Pharmacokinetics of Poziotinib in Healthy Adult Participants PHASE1 The purpose of the study is to evaluate the effect of multiple-doses of itr...
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Celerion, Phoenix clinical facility
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Study of Poziotinib in Participants With HER2-Positive Metastatic Breast Cancer PHASE2 The purpose of this study is to establish the dose regimen and evaluate the...
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Clearview Cancer Center
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Phase 2 Study of Poziotinib in Participants With NSCLC Having EGFR or HER2 Exon 20 Insertion Mutation PHASE2 This is a Phase 2, open-label, multi-center study to evaluate the efficacy ...
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Mayo Clinic Hospital
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Poziotinib in Stage IV Lung Adenocarcinoma With HER2 Mutation (KASTT001) PHASE2 In this trial, treatment efficacy and safety of Poziotinib will be assessed...
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Korean Association for the Study of Targeted Therapy
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A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies PHASE2 This is a Phase 2, open-label, multicenter study whose principal objectives...
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Pacific Shores Medical Group
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Study of Poziotinib in Japanese Patients With NSCLC PHASE1 A Phase 1/2, open-label, multicenter study to determine dose, tolerability,...
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National Cancer Center East
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