Found 38 matching trials
Study Evaluating The Tolerability Of Multiple Doses Of HKI-272
PHASE1Study to investigate the occurence of diarrhea after either once daily or t...
Location
Multiple Locations
Study Evaluating The PK And Safety Of Neratinib In Healthy Subjects And Subjects With Chronic Liver Disease
PHASE1The purpose of this study is to assess the pharmacokinetics of neratinib an...
Location
Pfizer Investigational Site
Study Evaluating Neratinib Plus Paclitaxel VS Trastuzumab Plus Paclitaxel In ErbB-2 Positive Advanced Breast Cancer
PHASE2This study is investigating the effects of an experimental drug (neratinib)...
Location
Ventura County Hematology-Oncology Specialists
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
PHASE2This ComboMATCH patient screening trial is the gateway to a coordinated set...
Location
University of Alabama at Birmingham Cancer Center
Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast Cancer
PHASE1This is an open-label, single arm, multi-center, multi-national, adaptive d...
Location
Western Regional Medical Center, Inc.
A Single Dose Bioequivalence Study Of Neratinib In Healthy Subjects
N/AThe purpose of the study is to demonstrate the bioequivalence of the propos...
Location
Investigational Site
HKI-272 Ketoconazole Drug Interaction Study
PHASE1To investigate a potential pharmacokinetic drug interaction between HKI-272...
Location
Multiple Locations
Study Evaluating The Effect Of A High-Fat Meal On The Pharmacokinetics Of Neratinib
PHASE1This study is being conducted to see if neratinib is absorbed, distributed,...
Location
Multiple Locations
A Phase 1/2 Study of HKI-272 (Neratinib) in Combination With Paclitaxel (Taxol) in Subjects With Solid Tumors and Breast Cancer
PHASE1The purpose of this study is to learn whether it is safe and effective to a...
Location
Scripps, Clinic General
Study to Examine the Effect of HKI-272 on Rhythms of the Heart (Cardiac Repolarization)
PHASE1The purpose of this study is to determine whether HKI-272 affects the rhyth...
Location
Multiple Locations