Found 340 matching trials
AR-42 and Decitabine in Treating Patients With Acute Myeloid Leukemia
PHASE1This phase I trial studies the side effects and best dose of AR-42 when giv...
Location
Cincinnati Children's Hospital
Safety, Tolerability and Pharmacokinetics of Quisinostat, a Histone Deacetylase Inhibitor, in Combination With Chemotherapy
PHASE1Quisinostat besides its own efficacy, which can potentially lead to better ...
Location
Russian Oncological Research Center n.a. N. N. Blokhin RAMS
Phase I Vorinostat in Combination With Niacinamide and Etoposide for Lymphoid Malignancies
PHASE1The purpose of this study is to test the safety of a combination of two ant...
Location
Center for Lymphoid Malignancies at CUMC
Oral LBH589 in Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL)
PHASE2The purpose of the study is to find out the effects and the safety of an in...
Location
H. Lee Moffitt Cancer Center and Research Institute
A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers
PHASE1BACKGROUND:
* The histone deacetylase (HDAC) inhibitors are a novel class ...
Location
National Institutes of Health Clinical Center, 9000 Rockville Pike
Study of Valproic Acid to Treat HIV Infected Adults
PHASE1A histone deacetylase (HDAC) inhibitor is a class of drug that interferes w...
Location
University of North Carolina Memorial Hospital
Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Melanoma
PHASE2Primary objective: To evaluate the efficacy of two different dosing schedul...
Location
Multiple Locations
Pasireotide, Everolimus and Selective Internal Radioembolization Therapy for Unresectable Hepatic Metastases
PHASE1The purpose of this study is to see the safety and activity of using pasire...
Location
Emory University Winship Cancer Institute
Azacitidine and Entinostat in Treating Patients With Recurrent Advanced Non-Small Cell Lung Cancer
PHASE1This phase I/II trial is studying the side effects and best dose of azaciti...
Location
USC Norris Comprehensive Cancer Center
Research In Viral Eradication of HIV Reservoirs
PHASE2This study will be a two-arm prospective 1:1 randomised controlled trial co...
Location
Brighton and Sussex University Hospitals NHS Trust