Found 23 matching trials
Intraperitoneal Injection of Oncolytic Viruses H101 for Patients With Refractory Malignant Ascites PHASE2 Assessment of effectiveness, safety and local immune activation of Oncolyti...
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Fudan University Shanghai Cancer Center
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Sequential T and I With H101 Via HAI for BCLC C Stage HCC: A Prospective Single-Center Single-Arm Pilot Study PHASE2 Indication: Hepatocellular carcinoma (HCC) patients at Barcelona Clinic Liv...
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The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital
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Oncolytic Virus (H101) + SBRT + Chemotherapy + Targeted Therapy + Immunotherapy for Unresectable CRLM PHASE2 This prospective study aims to investigate the efficacy and safety of perit...
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Sixth Affiliated Hospital, Sun Yat-sen University
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Intra-tumor Injection of Oncolytic Viruses H101 Combined With or Without Radiotherapy in Refractory/Recurrent Gynecological Malignancies PHASE2 The purpose of this clinical trial is to evaluate the effectiveness and saf...
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The First Affiliated Hospital of Xi'an Jiao Tong University
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Efficacy and Safety of Intratumoral Injection of Recombinant Human Adenovirus Type 5 Combined With Tislelizumab and Lenvatinib in the Treatment of Advanced Hepatocellular Carcinoma PHASE2 This prospective, single-arm study was aimed to evaluate the efficacy of re...
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Multiple Locations
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A Prospective, Multicenter, Single-Arm Phase II Exploratory Study of Serplulimab Combined With Oncolytic Virus H101, Short-Course Radiotherapy, and XELOX Chemotherapy as Total Neoadjuvant Treatment for Locally Advanced (cT1-3N0M0) Rectal Cancer PHASE2 This study aims to evaluate the safety and effectiveness of a combination t...
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Chongqing University Cancer Hospital
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Oncolytic Virus H101 Combined With Lenvatinib Plus Toripalimab Compared With FOLFOX in Patients With Advanced Biliary Tract Cancer (OPTIONS-06) PHASE2 This study will evaluate the efficacy and safety of Oncolytic virus H101 co...
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Zhongshan Hospital, Fudan University
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Effect and Safety of Recombinant Human Adenovirus Type 5 in Advanced HCC With Stable Disease After Sorafenib Treatment PHASE4 Sorafenib, as a first-line treatment for patients with advanced HCC, can si...
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Shaanxi Provincial People's Hospital
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H101 Combined With TACE for Primary Hepatocellular Carcinoma With Portal Vein Thrombosis PHASE2 This study is the first to compare the efficacy and safety of recombinant h...
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Multiple Locations
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Oncolytic Virotherapy Combined With Tislelizumab Plus Lenvatinib in Patients With Advanced Biliary Tract Cancer (OPTIONS-05) PHASE2 The objective of this study is to evaluate the efficacy and safety of oncol...
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Fudan University Shanghai Cancer Center
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