Found 15 matching trials
UGT1A1 Genotype-drien Phase I Study of Irinotecan in VIT Regimen for the Treatment of Pediatric R/R Solid Tumors PHASE1 Irinotecan is a commonly used salvage chemotherapy drug for children with r...
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Sun Yat-sen University Cancer Center
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Pharmacogenomics for Antidepressant Guidance and Education N/A More than one out of three individuals treated for major depressive disorde...
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Massachusetts General Hospital
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Clarification of Optimal Anticoagulation Through Genetics PHASE3 Individuals taking warfarin often need frequent dose changes as the interna...
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University of Alabama at Birmingham
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Isoniazid Dosage Prediction Model Development NA Isoniazid (INH) is an essential component of first-line anti-tuberculosis (...
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Samsung Medical Center
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Genotype-Guided Warfarin Therapy Trial NA The purpose of the investigators' study is to determine the clinical utilit...
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UNC Hospitals, UNC Anticoagulation Clinic at the Ambulatory Care Center (ACC), UNC Family Medicine Center Anti-coagulation Clinic
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Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients PHASE4 The purpose of this study is to determine whether pharmacogenetic guided do...
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Institute of geriatric Cardiology, General Hospital of People's Liberation Army
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Pharmacogenetic Dosing of Warfarin PHASE3 Purpose:
Warfarin is now the most commonly used oral anticoagulant. This d...
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Kaohsiung Medical University
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Biomarkers and Pharmacogenomics for Precision Depression Therapy NA Background: The clinical management of major depressive disorder (MDD) is h...
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Multiple Locations
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Applying Pharmacogenetic Algorithms to Individualize Dosing of Warfarin PHASE2 The purpose of this study is to determine whether DNA analysis improves the...
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Intermountain Healthcare Hospitals and Clinics
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Efficacy of Achieving Early Target Trough Levels of Tacrolimus Using CYP3A5 Guided Dosing Versus Weight-based Dosing in a Multi-ethnic Population of Kidney Transplant Recipients in Singapore NA The investigators hypothesise that the adaptation of CYP3A5 genotype-based ...
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Singapore General Hospital
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