Found 8 matching trials
Dose-finding Study of GSK2636771 When Administered in Combination With Enzalutamide in Male Subjects With Metastatic Castration-Resistant Prostate Cancer PHASE1 This Phase I, open-label, dose-finding, multicenter study is designed to de...
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GSK Investigational Site
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A Phase I/IIa, First Time in Human, Study of GSK2636771 in Subjects With Advanced Solid Tumors With Phosphatase and Tensin Homolog (PTEN) Deficiency PHASE1 The study consists of a pre-screening period to determine if the subject's ...
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GSK Investigational Site
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Study of the Selective PI3K-Beta Inhibitor GSK2636771 in Combination With Pembrolizumab in Patients With Metastatic Melanoma and PTEN Loss PHASE1 The goal of this clinical research study is to learn if GSK2636771 given in...
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University of Texas MD Anderson Cancer Center
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Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) PHASE2 This phase II MATCH screening and multi-sub-trial studies how well treatmen...
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University of Alabama at Birmingham Cancer Center
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Testing GSK2636771 as a Potential Targeted Treatment in Cancers With PTEN Loss of Expression (MATCH-Subprotocol P) PHASE2 This phase II MATCH treatment trial identifies the effects of GSK2636771 in...
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Active Not Recruiting
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ECOG-ACRIN Cancer Research Group
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PI3Kฮฒ Selective Inhibitor With Paclitaxel, Advanced Gastric Adenocarcinoma PHASE1 This is a Phase Ib/IIa, open-label, non-randomized, dose-escalation, multi-...
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Severance Hospital, Yonsei University Health System, Yonsei Cancer Center
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Testing GSK2636771 as a Potential Targeted Treatment in Cancers With PTEN Genetic Changes (MATCH-Subprotocol N) PHASE2 This phase II MATCH treatment trial identifies the effects of GSK2636771 in...
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Active Not Recruiting
Location
ECOG-ACRIN Cancer Research Group
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Biomarker-Integrated Umbrella, Advanced Gastric Cancer NA In-depth understanding of molecular characteristics of gastric cancer enabl...
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Severance Hospital, Yonsei University Health System, Yonsei Cancer Center
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