Found 12 matching trials
Safety, Pharmacokinetics (PK) of AKT and MEK Combination PHASE1 This study is a Phase 1 dose-escalation open-label study to determine the r...
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GSK Investigational Site
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Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Metastatic Triple-Negative Breast Cancer PHASE2 This phase II trial studies how well trametinib and v-akt murine thymoma vi...
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MedStar Georgetown University Hospital
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GSK1120212+GSK2141795 for Cervical Cancer PHASE2 This research study is evaluating the combination of two drugs called GSK11...
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Dana-Farber Cancer Institute
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Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Relapsed or Refractory Multiple Myeloma PHASE2 This phase II trial studies how well trametinib and Akt inhibitor GSK214179...
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Foothills Hospital
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Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer PHASE1 This phase I/II trial studies the side effects and the best dose of uproser...
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USC / Norris Comprehensive Cancer Center
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Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Acute Myeloid Leukemia PHASE2 This phase II trial studies how well trametinib and protein kinase B (Akt) ...
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University of Chicago Comprehensive Cancer Center
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Trametinib With or Without GSK2141795 in Treating Patients With Metastatic Uveal Melanoma PHASE2 This randomized phase II trial studies how well trametinib with or without ...
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Active Not Recruiting
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Emory University Hospital/Winship Cancer Institute
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Trametinib With GSK2141795 in BRAF Wild-type Melanoma PHASE2 This is a multicenter phase II clinical study of trametinib in combination ...
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University of California, San Francisco
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Trametinib With or Without GSK2141795 in Treating Patients With Recurrent or Persistent Endometrial Cancer PHASE1 This randomized phase I trial studies how well trametinib with or without G...
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Hartford Hospital
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An Open Label Study To Investigate the Pharmacokinetics and Pharmacodynamics of Repeat Escalating Doses of the Oral AKT Inhibitor GSK2141795 by 18F FDG PET Analysis in Subjects With Ovarian Cancer PHASE1 The purpose of this study is to explore the potential dose response relatio...
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GSK Investigational Site
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