Found 15 matching trials
Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy PHASE2 This phase II/III trial studies how well daunorubicin and cytarabine with o...
Show More Status
Active Not Recruiting
Location
University of Arkansas for Medical Sciences
Learn More & Join Trial
Study to Evaluate the Efficacy of Uproleselan in Combination With Chemotherapy in Chinese Patients With R/R AML PHASE3 This bridging study will evaluate the efficacy of uproleselan, a specific E...
Show More Location
Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Learn More & Join Trial
Placebo-controlled Single Dose Study to Evaluate Safety and Pharmacokinetics of GMI-1271 in Healthy Volunteers PHASE1 The purpose of this study is to evaluate safety, tolerability and pharmacok...
Show More Learn More & Join Trial
Safety, Tolerability and Efficacy of Uproleselan (GMI-1271) in Patients With COVID-19 Pneumonia PHASE1 The purpose of this study is to find out whether the drug uproleselan can h...
Show More Location
The University of Michigan
Learn More & Join Trial
A Study to Determine the Efficacy, Safety and Pharmacokinetics of GMI-1271 as Adjunct to Standard of Care for the Treatment of Multiple Myeloma PHASE1 This study will evaluate GMI-1271, a specific E-selectin antagonist, in mul...
Show More Learn More & Join Trial
Uproleselan (GMI-1271) for GI Toxicity Prophylaxis During Melphalan-Conditioned Autologous Hematopoietic Cell Transplantation (Auto-HCT) for Multiple Myeloma (MM) PHASE2 The investigators hypothesize that prophylactic E-selectin inhibition via a...
Show More Location
Washington University School of Medicine
Learn More & Join Trial
A Study to Evaluate the PK, Safety and Tolerability of GMI-1271 With and Without Filgrastim in Healthy Adult Subjects PHASE1 Phase 1, open-label, parallel, active-controlled, multiple IV dose, proof o...
Show More Learn More & Join Trial
Study to Evaluate PK and Safety With Uproleselan Combined With Chemotherapy to Treat Chinese R/R AML Patients PHASE1 This study will evaluate the safety and tolerability of uproleselan(GMI-127...
Show More Location
Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Learn More & Join Trial
Uproleselan, Cladribine, and Low Dose Cytarabine for the Treatment of Patients With Treated Secondary Acute Myeloid Leukemia PHASE1 This phase Ib/II trial finds out the best dose and effect of cladribine and...
Show More Location
M D Anderson Cancer Center
Learn More & Join Trial
Uproleselan, Azacitidine, and Venetoclax for the Treatment of Treatment Naive Acute Myeloid Leukemia PHASE1 This phase I trial evaluates the side effects of uproleselan, azacitidine, ...
Show More Location
University of California Davis Comprehensive Cancer Center
Learn More & Join Trial