Found 11 matching trials
Bioavailability Study Of PF-00868554 Administered As 3x250mg Oral Tablets (Wet Granulate, 3x250mg Oral Tablets (Dry Granulate) And 750mg Solution Under Fed State PHASE1 This study will test two different formulations. The results will be used t...
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Investigation Of The Effect Of Steady State Filibuvir On The Pharmacokinetics Of Oral Contraceptives (Levonorgestrel And Ethinyl Estradiol) PHASE1 The purpose of this study is to estimate the effect of filibuvir on the pha...
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Phase 1 Study To Evaluate Antiviral Activity Of Small Molecule Direct Antiviral Agent At Multiple Doses In Subjects With Chronically Infected Hepatitis C Virus. PHASE1 Phase 1 study in HVC (Hepatitis C Virus) infected subjects to determine pha...
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Drug Interaction Study Of Filibuvir With Methadone Among Subjects On Chronic Methadone Maintenance PHASE1 Filibuvir, a CYP3A4 inhibitor is being developed for the treatment of chron...
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A Phase 1 Study Of PF-00868554 In Hepatitis C Virus (HCV) Positive Patients PHASE1 Assess the safety, tolerability and pharmacokinetics of multiple oral doses...
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A Dose Ranging Study Of PF-00868554 In Combination With PEGASYS And COPEGUS In Patients With Chronic Hepatitis C Genotype 1 Infection PHASE2 The purpose of this study is to further assess the potency of PF-00868554, ...
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Radiolabel ADME (Absorption, Distribution, Metabolism, and Excretion) Study Of [14C] PF-00868554 In Healthy Adult Male Subjects PHASE1 This is a phase 1 study to assess the routes of elimination of a single ora...
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Study To Assess The Impact Of Hepatic Impairment On The Safety, Tolerability And Pharmacokinetics Of Single-Dose 200 Mg Of PF-868554 PHASE1 The metabolism of PF-00868554 is primarily mediated by CYP3A, and it is ant...
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A Study To Investigate Safety And Pharmacokinetics Of A Single Dose Of PF-00868554 (Filibuvir) In Japanese Healthy Adult Volunteers PHASE1 A single dose of PF-00868554 (filibuvir) will be safety and tolerable in Ja...
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Filibuvir In Treatment Naive Hepatitis C Virus (HCV) Genotype 1 Subjects PHASE2 The primary objective for this study is to determine if the addition of fil...
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