Found 12 matching trials
Evaluation of Immediate Release Tablet
PHASE1Single dose comparison of liquid and solid formulation, followed by study o...
Location
Quotient Clinical
Pharmacokinetics of IV Formulation
PHASE1Open label evaluation of a single intravenous dose of F901318 to healthy ma...
Location
Multiple Locations
A Phase I Study to Assess the Pharmacokinetics of Olorofim in Subjects With Hepatic Impairment
PHASE1A single oral dose study to investigate the PK and safety of olorofim in mi...
Location
Orange County Research Centre
Drug/Drug Interactions With F901318
PHASE1Study of interactions between F901318 and multiple doses of posaconazole an...
Location
Multiple Locations
Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects
PHASE1A Phase I, open label study evaluating safety, tolerability and pharmacokin...
Location
Covance Clinical Research Unit
Safety and Pharmacokinetics of Oral F901318 (Fluconazole and Posaconazole) IN Aml Leukaemia
PHASE1Non-randomized, multi-centre, open label, uncontrolled, multiple dose, phas...
Location
Multiple Locations
Evaluation of the Potential for Cytochrome P450 3A4 Inhibition by F901318 Using Oral Midazolam as a Probe
PHASE1Open label evaluation of potential interaction of F901318 with cytochrome P...
Location
Hammersmith Medicines Research
Single Ascending Oral Dose Study of F901318
PHASE1Double blind, placebo controlled, ascending single oral dose, sequential gr...
Study on Safety and Pharmacokinetics of Intravenous F901318 for Fungal Prophylaxis in AML Patients
PHASE1This study assesses the pharmacokinetics and safety of the new antifungal F...
Location
Multiple Locations
Drug-drug Interaction (DDI) Study to Assess Effect of Itraconazole and Rifampicin Upon Olorofim
PHASE1This is a Phase 1, single-centre, fixed-sequence, open label, drug-drug int...
Location
Hammersmith Medicines Research