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The Link Between Mental Imagery and the Reduction of Fear in Imaginal Extinction
NAImaginal exposure is a widely used psychological treatment technique. Imagi...
Location
Uppsala University, Departement of Psychology
Effect of Orexin System on Nicotine Addiction and Its Neural Mechanism
NAThe goal of this clinical trial is to reveal the role and mechanism of orex...
Location
Shenzhen Kangning Hospital
Testing and Development of a Sleep Training Mobile Health Application
NAThe specific aims of this study are : 1) To pilot test the alpha build prot...
Location
Multiple Locations
Behavioral Memory Modulation in Nicotine Addiction
NAThe purpose of the study is to see if a behavioral intervention known as re...
Location
Medical University of South Carolina
Measurement of Treatment Effects
EARLY_PHASE1The overall objective is to evaluate and compare the efficacy of two common...
Location
Multiple Locations
Evaluation of the Effect of a Psychological Program for Children With Autism Spectrum Disorder and Feeding Difficulties
NAFeeding difficulties are frequent in children with Autism Spectrum Disorder...
Location
Department of Child and Adolescent Mental Health. Hospital Sant Joan de Déu
Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSD.
PHASE2Purpose: About 6.4% of the U.S. population suffers from posttraumatic stres...
Location
Massachusetts General Hospital
Treatments Being Tested
Experiment 1: Three-day aversive conditioning, extinction, and extinction retention testing paradigmAllopregnanolone (Allo) with 6% USP Dexolve (sulfobutyl ether-beta-cyclodextrin sodium salt) in 0.9% saline for IV infusion will be provided by the University of California, Davis, GMP manufacturer.Experiment 1. Three-day aversive conditioning, extinction, and extinction retention testing paradigmMatching IV PlaceboExperiment 2. Three-day aversive conditioning, reconsolidation blockade, and testing paradigmAllopregnanolone (Allo) with 6% USP Dexolve (sulfobutyl ether-beta-cyclodextrin sodium salt) in 0.9% saline for IV infusion will be provided by the University of California, Davis, GMP manufacturer.Experiment 2. Three-day aversive conditioning, reconsolidation blockade, and testing paradigmMatching IV Placebo Optimizing Exposure Using Occasional Aversive Imagery in Spider Fearful Individuals
NAThe effectiveness of an optimized extinction training is investigated in sp...
Location
Philipps-University Marburg
Motivational Refinements for Facilitating Reinforcement Schedule Thinning
NADestructive behavior represents a comorbid condition of developmental disab...
Location
Douglass Developmental Disabilities Center
Cognitive Control Training for Extinction in PTSD
NAThe proposed study will test whether a working memory training (WMT) progra...
Location
VA San Diego Healthcare System, San Diego, CA