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Abemaciclib for the Treatment of Luminal Metastatic breAst caNcer in the Real-life Clinical pracTice in Russia. N/A The ATLANT study is prospective, multicentre, non-interventional, observati...
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Russian Society of Clinical Oncology
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Endocrine Therapy Plus CDK4/6 in First or Second Line for Hormone (SONIA) Receptor Positive Advanced Breast Cancer PHASE3 Given the uncertain benefit in efficacy of adding CDK 4/6 to first rather t...
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Jeroen Bosch Ziekenhuis
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Predicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 Study N/A PALMARES-2 is a retrospective/prospective, observational, multicenter, popu...
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Centro di Riferimento Oncologico IRCCS
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A Vaccine (STEMVAC) With Standard Endocrine-Based Therapy or Chemotherapy for the Treatment of Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer PHASE2 This phase II trial studies how well a vaccine, STEMVAC, works in combinati...
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Fred Hutch/University of Washington Cancer Consortium
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Adjuvant CDK4/6 Inhibitor Use in HR+/HER2- Breast Cancer N/A To evaluate the efficacy and safety of adjuvant CDK4/6 inhibitors in patien...
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Renji Hospital, School of Medicine, Shanghai Jiaotong University
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Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer. PHASE2 This phase IIa trial studies the side effects of abemaciclib monotherapy in...
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City of Hope Medical Center
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Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer PHASE3 This study will evaluate the effect of adding abemaciclib to fulvestrant fo...
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St. Joseph's Hospital and Medical Center
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Pragmatic Study to Optimize Neoadjuvant Treatment and Surgical De-escalation in HR+/HER2- Early Breast Cancer Using Oncotype DX and Abemaciclib PHASE2 This is a pragmatic phase 2 study to determine the proportion of patients w...
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Istituto di Ricerche Farmacologiche Mario Negri IRCCS
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DiviTum®TKa: A Biomarker Assay for Efficacy in HR+ Breast Cancer Patients N/A This study is being done to determine if there is a pattern associated with...
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Mayo Clinic in Florida
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Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer NA The purpose of this study is to evaluate the efficacy and safety of ctDNA-g...
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Mayo Clinic Arizona
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