Found 21 matching trials
A Phase I Study of the Pharmacokinetic Variability and Relative Bioavailability of the Phase 3 and Common Blend Formulations of Eliglustat in Healthy Adult Subjects PHASE1 The primary objective of this pilot study is to determine the within-subjec...
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A Study of the Efficacy and Safety of Eliglustat Tartrate (Genz-112638) in Type 1 Gaucher Patients PHASE2 Gaucher disease is a genetic disease that results in a deficiency of an enz...
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New York University
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Safety and Efficacy of Eliglustat With or Without Imiglucerase in Pediatric Patients With Gaucher Disease (GD) Type 1 and Type 3 PHASE3 Primary Objective:
Evaluated the safety and pharmacokinetics of eliglustat...
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Investigational Site Number : 0320001
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A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease to Evaluate Once Daily Versus Twice Daily Dosing (EDGE) PHASE3 The primary objective of this study was to evaluate the efficacy and safety...
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University of California, San Diego Medical Center
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A Study to Evaluate Pharmacokinetic Parameters of Eliglustat in Healthy Volunteers Who Are CYP2D6 Extensive or Poor Metabolizers PHASE1 The primary objective of the study is to evaluate dose proportionality and ...
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M.D.Covance Clinical Research Unit 1341 W
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GSL Synthetase Inhibitor Eliglustat Combined With CD30 Target Immunotherapy for the Treatment of of CD30+ Lymphoma PHASE1 Targeted therapy against the CD30 molecule has achieved some progress in CD...
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People's Liberation Army General Hospital
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A Phase 1 Study Evaluating Eliglustat's Effects on Pharmacokinetics, Safety & Tolerability of Digoxin in Healthy Adults PHASE1 The primary objective of this study is to determine the effect of repeat or...
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PPD Phase I Clinic
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Study to Evaluate the Effect of Eliglustat on the Pharmacokinetics, Safety and Tolerability of Metoprolol in Healthy Adults PHASE1 The primary objective is to determine the effect of repeated oral doses of ...
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Multiple Locations
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GSL Synthetase Inhibitor Plus Immune Checkpoint Inhibitor and/or Regorafenib in Previously Treated pMMR/MSS CRC. PHASE2 In this single-center,open-label, randomized, phase II study, the efficacy ...
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A Study of the Effects of Renal Impairment on the Pharmacokinetics and Tolerability of Eliglustat Tartrate PHASE1 Primary Objective:
To study the effect of mild, moderate, and severe renal...
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Investigational Site Number 840004
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