Found 410 matching trials
Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung Cancer
PHASE2This phase II trial studies the effect of bintrafusp alfa with pemetrexed a...
Location
M D Anderson Cancer Center
Study of Osimertinib+Bevacizumab+Chemotherapy for EGFR+ Advanced Non-Small Cell Lung Cancer With Concurrent Mutations
PHASE2This is a single-center, open-label, phase I clinical trial aimed to evalua...
Location
Tianjin Medical University Cancer Institute and Hospital
Almonertinib Combined With Cerebral Radiation Treat Brain Metastases From EGFR Positive NSCLC
PHASE2According to literature reports, about 16.3%-19% of newly diagnosed NSCLC p...
Location
Chongqing University Cancer Hospital
A Study of FWD1509 in Adults With Non-Small Cell Lung Cancer
PHASE1The purpose of this study is to characterize the safety and tolerability of...
Location
Gabrail Cancer Center
Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations
PHASE1BDTX-1535-101 is an open-label, Phase 1 dose escalation and Phase 2 multipl...
Status
Active Not Recruiting
Location
University of Alabama
Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib
PHASE1The purpose of this randomized study is to determine the safety and efficac...
Location
Valkyrie Clinical Trials
A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations
PHASE1This Phase1/2, open label, multicenter study will assess the safety, tolera...
Location
Mayo Clinic Hospital - Arizona
Continuation of TKI With or Without Chemotherapy Beyond Gradual Progression
PHASE2There have been reports suggesting that continuous administration of epider...
Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy of NSCLC Patients in China
N/ATo evaluate the concordance of sensitizing mutations detected between paire...
Location
The First Affiliated Hospital of Guangzhou Medical University
A Study Comparing Pemetrexed Plus Cisplatin Versus Pemetrexed Alone in NSCLC Patients Who Have Progressed on First Line EGFR-TKI
PHASE2It has not been established whether platinum-based doublets is better than ...
Location
Samsung Medical Center