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Trial Search

Current Search Criteria:

Intervention: E5501

Found 17 matching trials

A Single-Center, Open-Label, Randomized, 3-Treatment Crossover Bioavailability Study of Single Oral Doses of E5501 Old Tablet Formulation Under Fasted Conditions and a New Tablet Formulation Under Fed and Fasted Conditions in Healthy Subjects

PHASE1

This study will be a single-center, open-label, randomized, 3-treatment cro...

Status

Completed

Location

Celerion

Start Date

2010-01

Trial ID

NCT01260155

Treatments Being Tested

E5501 E5501 E5501

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Once-daily Oral Avatrombopag in Japanese Subjects With Chronic Liver Diseases and Thrombocytopenia

PHASE2

This is a phase 2, randomized, double-blind, placebo-controlled, parallel g...

Status

Completed

Location

Multiple Locations

Start Date

2014-07

Trial ID

NCT02227693

Treatments Being Tested

avatrombopag Placebo

Single and Multiple Dose Asian Bridging Study

PHASE1

The purpose of this study is to evaluate the single-dose (SD) pharmacokinet...

Status

Completed

Location

Parexel International, Early Phase Clinical Unit

Start Date

2010-07

Trial ID

NCT01251731

Treatments Being Tested

E5501 E5501 E5501 E5501

Subject Variability in Two Lots of E5501 Administered to Fed and Fasted Healthy Subjects

PHASE1

This will be a randomized, open-label, four-group, two-period, replicate de...

Status

Completed

Location

PRA Early Development Services

Start Date

2011-02

Trial ID

NCT01327872

Treatments Being Tested

E5501 40 mg 2 x 20-mg tablets, orally, fasted E5501 40 mg 2 x 20-mg tablets, orally, with food E5501 40mg 2 x 20-mg tablets, orally, fasted E5501 40 mg 2 x 20-mg tablets, orally, with food

Avatrombopag for the Treatment of Thrombocytopenia After Donor Hematopoietic Stem Cell Transplant

PHASE2

This phase II trial studies the side effects and how well avatrombopag work...

Status

Withdrawn

Location

Multiple Locations

Start Date

2022-12

Trial ID

NCT04312789

Treatments Being Tested

Avatrombopag

Phase 2, Parallel Group, Rollover Study of AKR-501 in Patients With ChronicITP Who Completed 28 Days of Study Treatment in Protocol 501-CL-003

PHASE2

The purpose of this study is to determine the safety and efficacy of AKR-50...

Status

Completed

Location

Pacific Cancer Medical Center, Inc

Start Date

2007-05

Trial ID

NCT00625443

Treatments Being Tested

Blinded (placebo)Open Label (Avatrombopag tablets)Blinded (Avatrombopoag tablets)

A Single-dose Study in Healthy Japanese Male Adults to Evaluate Pharmacokinetics and Pharmacodynamics of E5501 5 mg Tablet (Study E5501-J081-015)

PHASE1

E5501 (5 mg, 20 mg, and 40 mg) will be administered to healthy male adults ...

Status

Completed

Location

Multiple Locations

Start Date

2013-01

Trial ID

NCT01774773

Treatments Being Tested

Group A: E5501 5mg, then 20mg, then 40 mg, then 5mg Group B: E5501 20mg, then 40mg, then 5 mg, then 5mg Group C: E5501 40mg, then 5mg, then 20 mg, then 5mg

A Open-label, Three-period, Partial-replicate Design Study to Evaluate the Inter- and Intrasubject Variability of the Avatrombopag To-be-marketed Formulation Administered as Single Doses of 40 mg to Healthy Subjects Receiving a Low-fat Meal

PHASE1

A Randomized, Open-label, Three-period, Partial-replicate Design Study to E...

Status

Completed

Location

Celerion

Start Date

2012-10

Trial ID

NCT01759394

Treatments Being Tested

Avatrombopag maleate 40 mg

Once-Daily Oral Avatrombopag Tablets Used in Subjects With Chronic Liver Diseases and Thrombocytopenia Prior to Elective Surgical or Diagnostic Procedures

PHASE2

The purpose of this study is to evaluate the efficacy of once-daily Oral av...

Status

Completed

Location

Ochsner Clinic Foundation

Start Date

2009-05

Trial ID

NCT00914927

Treatments Being Tested

Avatrombopag Avatrombopag Placebo

Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazole, Itraconazole, or Rifampin in Healthy Subjects

PHASE1

The purpose of this study is to determine the effects of concomitant admini...

Status

Completed

Location

Multiple Locations

Start Date

2016-04

Trial ID

NCT02809768

Treatments Being Tested

Avatrombopag Fluconazole Itraconazole Rifampin

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