Found 7 matching trials
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Donidalorsen (IONIS-PKK-LRx) Administered Subcutaneously to Healthy Volunteers
PHASE1The purpose is to assess the Safety, Tolerability, Pharmacokinetics, and Ph...
Location
Ionis Investigative Site
A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)
PHASE3The purpose of this study is to evaluate the long-term safety and efficacy ...
Status
Active Not Recruiting
Location
Ionis Investigative Site
A Study to Assess the Clinical Efficacy of Donidalorsen (Also Known as IONIS-PKK-LRx and ISIS 721744) in Participants With Hereditary Angioedema
PHASE2The purpose of this study was to evaluate the clinical efficacy, safety, an...
Location
Medical Research of Arizona
Donidalorsen Expanded Access Program for Patients With Hereditary Angioedema
N/AThe purpose of the Expanded Access Program is to provide pre-approval acces...
Location
Multiple Locations
OASIS-HAE: A Study to Evaluate the Safety and Efficacy of Donidalorsen (ISIS 721744 or IONIS-PKK-LRx) in Participants With Hereditary Angioedema (HAE)
PHASE3The purpose of this study was to evaluate the safety and efficacy of donida...
Location
Ionis Investigative Site
An Extension Study of Donidalorsen (IONIS-PKK-LRx) in Participants With Hereditary Angioedema
PHASE2The purpose of this study was to evaluate the safety and efficacy of extend...
Location
Ionis Investigative Site
Donidalorsen Treatment in Children With Hereditary Angioedema
PHASE3The purpose of this study is to evaluate the safety, tolerability and pharm...
Location
Ionis Investigative Site