Found 7 matching trials
Multicenter Phase 1b Trial Testing the Neoadjuvant Combination of Domatinostat, Nivolumab and Ipilimumab in IFN-gamma Signature-low and IFN-gamma Signature-high RECIST 1.1-measurable Stage III Cutaneous or Unknown Primary Melanoma PHASE1 DONIMI is a phase 1b trial testing the combination of domatinostat + nivolu...
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Melanoma Institute Australia
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4SC-202 in Combination With Pembrolizumab in Patients Primary Refractory/Non-responding to Prior Anti-PD-1 Therapy PHASE1 Phase Ib/II open-label, multi-center study with a priming cycle of 4SC-202 ...
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Universitätsklinikum Essen
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Epigenetic Modulation of the immunE Response in GastrointEstinal Cancers (EMERGE) PHASE2 A multicenter phase II non-randomised trial assessing the efficacy of domat...
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The Royal Marsden Hospital NHS Foundation Trust
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Domatinostat in Combination With Avelumab in Patients With Advanced Merkel Cell Carcinoma Progressing on Anti-PD-(L)1 PHASE2 This phase II trial studies how well domatinostat (4SC-202) works in combin...
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Domatinostat in Combination With Avelumab in Patients With Treatment-naïve Metastatic Merkel Cell Carcinoma (MERKLIN 1) PHASE2 This phase II trial studies how well domatinostat (4SC-202) works in combin...
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Multiple Locations
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Oral Histone Deacetylase Inhibitor 4SC-202 in Patients With Advanced Hematologic Malignancies (TOPAS) PHASE1 The purpose of this study is to determine the Maximum Tolerated Dose, Dose ...
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Universiätsklinikum Köln
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Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma PHASE1 This is a multicenter, open-label, Phase 1/2 study evaluating the safety, t...
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Moffitt Cancer Center
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