Found 39 matching trials
Drug-drug Interaction Study of GSK1278863 With Pioglitazone, Rosuvastatin and Trimethoprim in Healthy Adult Volunteers PHASE1 This study will be a two-part with an open-label, single oral dose, two-way...
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Relative Bioavailability Study for GSK1278863A PHASE1 A randomized, open-label, 3-period crossover study....
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Anemia Study in Chronic Kidney Disease (CKD) : Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat -Forearm Blood Flow (ASCEND-FBF) PHASE2 Daprodustat has demonstrated an ability to effectively raise hemoglobin con...
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Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Single and Repeated Doses of Topical GSK1278863 PHASE1 This is a randomized, placebo-controlled, single-blind (subjects and invest...
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Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Three-times Weekly Dosing of GSK1278863 in Hemodialysis-dependent Subjects With Anemia Associated With Chronic Kidney Disease Who Are Switched From a Stable Dose of an Erythropoiesis-stimulating Agent PHASE2 GSK1278863 is an orally available, hypoxia-inducible factor - prolyl hydrox...
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Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-in Incident Dialysis (ASCEND-ID) PHASE3 The purpose of this multi-center study is to evaluate the efficacy and safe...
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Anemia Studies in CKD: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat- Iron (ASCEND: Fe) PHASE2 Daprodustat administration has the potential, by virtue of increasing hypox...
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REDCURE Registry for Chronic Kidney Disease (CKD) Anemia N/A A local registry on CKD-associated anemia aims to provide real-world insigh...
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Absorption and Elimination of Radiolabeled Daprodustat PHASE1 Absorption, metabolism and excretion of daprodustat (GSK1278863) have been ...
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Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat in Non-Dialysis Subjects Evaluating Hemoglobin (Hgb) and Quality of Life (ASCEND-NHQ) PHASE3 The purpose of this multi-center study in non-dialysis participants with an...
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