Found 14 matching trials
Study of AZD9150 and MEDI4736 (Durvalumab) in Japanese Adult Patients With Advanced Solid Malignancies PHASE1 This is a phase I, open-label study to assess the safety, tolerability, pha...
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AZD9150 Plus Durvalumab Alone or in Combination With Chemotherapy in Patients With Advanced, Solid Tumours and in Patients With Non-Small-Cell Lung Cancer PHASE1 This is a phase Ib/II, open-label multicentre study to assess the safety, t...
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A Study of Novel Anti-cancer Agents in Patients With Previously Untreated NSCLC PHASE1 This study is designed to determine the efficacy and safety of durvalumab a...
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Active Not Recruiting
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AZD9150, a STAT3 Antisense Oligonucleotide, in People With Malignant Ascites PHASE2 Background:
\- Some people with gastrointestinal or ovarian cancer also ha...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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MEDI4736 Alone and in Combination With Tremelimumab or AZD9150 in Adult Subjects With Relapsed/Refractory DLBCL (D4190C00023) PHASE1 The purpose of this study is to evaluate the safety, tolerability, and effi...
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Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy PHASE2 This is an open-label, multi-centre, umbrella Phase II study in participant...
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Active Not Recruiting
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Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AML PHASE1 This is a Phase 1 study investigating the safety and efficacy of Danvatirse...
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Montefiore Medical Center
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Activity and Safety of Danvatirsen and Pembrolizumab in HNSCC PHASE2 Open-label, Phase II, randomized, controlled study evaluating the efficacy ...
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The University of Arizona Cancer Center
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Study to Assess MEDI4736 With Either AZD9150 or AZD5069 in Advanced Solid Tumors & Relapsed Metastatic Squamous Cell Carcinoma of Head & Neck PHASE1 This multicentre, open-label, Phase 1b/2 study is designed as a 2 part stud...
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A Phase I/Ib Study of AZD9150 (ISIS-STAT3Rx) in Patients With Advanced/Metastatic Hepatocellular Carcinoma PHASE1 This is a phase I/Ib open-label, multicentre study to assess the safety, to...
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