Found 30 matching trials
A Long-Term Treatment Study of ACH-0144471 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) PHASE2 The purpose of this study is to evaluate the long-term safety and efficacy ...
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ACTIV-5 / Big Effect Trial (BET-C) for the Treatment of COVID-19 PHASE2 This is a platform trial to conduct a series of randomized, double-blind, p...
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University of Alabama at Birmingham School of Medicine - Infectious Disease
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A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN PHASE2 The primary objective of this study was to determine whether ACH-0144471 (a...
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A Study of Danicopan in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration PHASE2 This is a dose finding study designed to evaluate the efficacy, safety, and...
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Assess Long-Term Safety of Danicopan Add-on Therapy in Participants With Paroxysmal Nocturnal Hemoglobinuria: Analysis of IPIG-Registry Data N/A This is a noninterventional registry-based cohort study utilizing data coll...
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Active Not Recruiting
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Clinical Research Site
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Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis PHASE3 The primary objective of this study is to evaluate efficacy of danicopan as...
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Study of Danicopan in Participants With Hepatic Impairment PHASE1 The purpose of this study was to evaluate the safety, tolerability, and pha...
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Study of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) PHASE2 The purpose of this study was to determine the safety and efficacy of ACH-0...
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A Drug Interaction Study Between Danicopan and Midazolam, Fexofenadine, and Mycophenolate Mofetil in Healthy Participants PHASE1 The purpose of this study was to determine the potential drug interaction b...
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A Study of the Cardiac Effects of Danicopan in Healthy Adults PHASE1 This was a randomized, double-blind, double-dummy, placebo- and positive-co...
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