Found 6 matching trials
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL343 in Healthy Volunteers
PHASE1This is a Phase 1 study carried out at a single site in 88 healthy male sub...
Location
Centre for Human Drug Research (CHDR)
HEALEY ALS Platform Trial - Regimen G DNL343
PHASE2The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen cl...
Location
Healey Center for ALS at Massachusetts General Hospital
A Study to Evaluate the Bioavailability and Safety of DNL343 in Healthy Volunteers
PHASE1This is a Phase 1 relative bioavailability study carried out in approximate...
Location
Auckland Clinical Studies Ltd.
A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-DNL343 Following a Single Oral Dose in Healthy Male Participants
PHASE1This is a Phase 1, open-label, nonrandomized, single-dose study in healthy ...
A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis
PHASE1This is a Phase 1b, multicenter, randomized, placebo-controlled, double-bli...
HEALEY ALS Platform Trial - Master Protocol
PHASE2The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen cl...
Status
Active Not Recruiting
Location
Barrow Neurological Institute