Found 124 matching trials
Pre-emptive Therapy With DEC-C to Improve Outcomes in MDS Patients With Measurable Residual Disease Post Allogeneic Hematopoietic Cell Transplant
PHASE1The investigators hypothesize that early measurable residual disease (MRD)-...
Location
Washington University School of Medicine
Combined Evaluation of Epigenetic and Sensitising Therapy in AML and MDS
PHASE1The goal of this project is to see if two new potential treatments (defacti...
Location
Prince of Wales Hospital
Combination Study of Guadecitabine/ASTX727 and Pembrolizumab
PHASE1HyPeR is a multi-centre Phase 1 Dose Escalation Study of Guadecitabine (SGI...
Status
Active Not Recruiting
Location
Royal Marsden Hospital
A Study of Pevonedistat Combined With Decitabine and Cedazuridine in Adults With Higher-risk Myelodysplastic Syndromes
PHASE2The main aim of the study is to see if signs and symptoms of myelodysplasti...
Location
Multiple Locations
The Study of ICP-248 in Patients With Mature B-cell Malignancies
PHASE1A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pha...
Location
The First Affiliated Hospital of Bengbu Medical College
Eltanexor (KPT-8602) With Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic Syndromes
PHASE1Background:
Myelodysplastic syndromes (MDS) are diseases that affect the b...
Location
National Institutes of Health Clinical Center
Venetoclax and ASTX727 for the Treatment of Relapsed, Refractory, or Newly Diagnosed Acute Myeloid Leukemia
PHASE2This phase II trial studies the possible benefits of venetoclax and ASTX727...
Status
Active Not Recruiting
Location
M D Anderson Cancer Center
A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors
PHASE1A phase 1/2a, open-label, first-in-human study mainly aimed to evaluate the...
Location
Local Institution - 0033
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
PHASE1Phase 1 dose escalation will determine the maximum tolerated dose (MTD) and...
Location
City of Hope Comprehensive Cancer Center
Oral Decitabine/Cedazuridine (DEC-C) in Combination With Nivolumab for Patients With Mucosal Melanoma
PHASE1Activation of the RIG-I innate immune pathway and increased expression of t...
Status
Active Not Recruiting
Location
University of Colorado Hospital