Found 10 matching trials
A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST)
PHASE2The primary objective of this trial is to evaluate the progress free surviv...
Location
Beijing Cancer Hospital
A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies
PHASE1This is a Phase 1, open-label, first-in-human (FIH) dose-escalation study d...
Location
Honor Health (GIST, mastocytosis, other solid tumors)
A Study to Assess DCC-2618 and Sunitinib in Patients With Advanced GIST After Treatment With Imatinib
PHASE2the primary objective of this study is to assess the efficacy (progression-...
Location
Beijing Cancer Hospital
Expanded Access Program of Ripretinib (DCC-2618) for the Treatment of Patients With Advanced GIST
N/AThis is an open-label, single-arm, multicenter expanded access study to pro...
Status
Approved For Marketing
Location
Multiple Locations
A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies
PHASE1This is a Phase 1/2, multicenter, open-label (unless otherwise specified in...
Location
University of Southern California - Norris Comprehensive Cancer Center
A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib
PHASE3This is a 2-arm, randomized, open-label, international, multicenter study c...
Status
Active Not Recruiting
Location
Mayo Clinic Scottsdale
Study of DCC-2618 in Patients With GIST After at Least 3 Prior Treatments
PHASE1To evaluate the safety of DCC-2618 in patients with unresectable, metastati...
Location
National Cancer Center Hospital East
Phase 3 Study of DCC-2618 vs Placebo in Advanced GIST Patients Who Have Been Treated With Prior Anticancer Therapies
PHASE3This is a 2-arm, randomized, placebo-controlled, double-blind, internationa...
A Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With Imatinib
PHASE3This is a Phase 3, 2-arm, randomized, open-label, global, multicenter study...
Status
Active Not Recruiting
Location
UC San Diego Moores Cancer Center
Ripretinib in Combination With Binimetinib in Patients With Gastrointestinal Stromal Tumor (GIST)
PHASE1Multicenter, open-label Phase 1b/2 study of ripretinib in combination with ...
Location
Multiple Locations