Found 18 matching trials
Pharmacokinetics of Rising Single-doses of BIA 6-512 and Their Effect on the Levodopa Pharmacokinetics PHASE1 To investigate the effect of rising oral single-doses of BIA 6-512 (25 mg, ...
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Human Pharmacology Unit (UFH)
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Efficacy and Safety Proof of Concept Study in Patients With Parkinson's Disease and End-of-dose Wearing-off (COMPOC) PHASE2 This will be a randomised, crossover, double-blind, double-dummy, active-co...
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Clinical Research Services Turku CRST
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PK, PD and Safety of Multiple Doses of V1512 Tablets in PD Patients Compared to Standard Levodopa/Carbidopa Oral Tablets PHASE1 The purpose of the study is to determine if the pharmacokinetic profile of ...
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IRCCS San Raffaele Pisana
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Levodopa Concentration Profile With Stalevo 75/125 mg PHASE1 The purpose of this study is to confirm that the dose levels and dosing fre...
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Phase I Unit, Orion Pharma
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Efficacy and Tolerability of Nebicapone in Parkinson's Disease Patients With "Wearingoff" Phenomenon PHASE2 The purpose of this study was to investigate the effect on the "wearing-off...
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Multiple Locations
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Comparing Different Levodopa/Carbidopa/Entacapone Treatment Regimens PHASE2 The primary objective is to assess the effect of a single dose of two exper...
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Kanta-Hämeen keskussairaala
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The Effect of BIA 9-1067 at Steady-state on the Levodopa Pharmacokinetics PHASE1 The purpose of this study is to determine the effect of repeated dosing of ...
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Clock and Narcolepsy Genetic Variants and the Effects of Stalevo® (Levodopa/Carbidopa/Entacapone) on Sleep Disorders in Parkinson's Disease NA The purpose of this study is to investigate the genetic variants of clock a...
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Asan Medical Center
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Carbidopa/Levodopa/Entacapone Versus Immediate Release (IR) Carbidopa/Levodopa on Non-motor Symptoms in Patients With Idiopathic Parkinson's Disease and Demonstrating Non-motor Symptoms of Wearing Off PHASE4 The purpose of this study is to test the effects of carbidopa/levodopa/enta...
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Intestinal Levodopa + Entacapone Therapy (Lecigon®) to Counteract Dopaminergic Desensitization and Neuropsychiatric Complications in Parkinson's Disease PHASE3 This study is a Phase III multicentric randomized controlled trial with par...
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DRK gemeinnützige Krankenhausgesellschaft mbH Saarland
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