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Study of Efficacy and Safety of NM8074 in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy PHASE2 This is a Phase II, open-label study designed to evaluate the safety, effic...
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Multiple Locations
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The Effect of Some Drugs Used in Treatment of Vasculitis on the Complement System in Children PHASE3 Vasculitis denotes affection of small to medium sized vessels by polyangiti...
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Assiut University Pediatric Hospital
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Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial) PHASE1 This Phase 1b basket trial will investigate the safety, tolerability, pharm...
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University of California-Irvine
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Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease PHASE2 This Phase 2 study is designed to assess the safety, efficacy, pharmacokine...
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ADARx Clinical Site
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Eculizumab For Acute Attack of Neuromyelitis Optica Spectrum Disorder PHASE2 Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing, inflammatory...
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Multiple Locations
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Research Into the Effect of a Clot-dissolving Agent and Its Inhibitor EARLY_PHASE1 Single-chain urokinase-type plasminogen activator (pro-urokinase) is a high...
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Center for Human Drug Research
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A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS) PHASE3 This study aims to evaluate the efficacy and safety of crovalimab in pediat...
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Children's Hospital Colorado
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Long-term Safety of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria PHASE2 This study was designed to provide continued access to BCX9930 for particip...
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Investigative Site
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Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis PHASE3 The purpose of this study is to evaluate the safety and efficacy of ALXN172...
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Active Not Recruiting
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Safety, Tolerability and Activity of BIVV009 in Healthy Volunteers and Patients With Complement Mediated Disorders PHASE1 Prospective, double-blind, randomized, placebo-controlled First-In-Human st...
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Medical University of Vienna
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