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ZIMURA in Combination With LUCENTIS in Patients With Neovascular Age Related Macular Degeneration (NVAMD) PHASE2 To assess the safety of intravitreal Zimura™ (complement factor C5 inhibito...
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Retinal Research Institute
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A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibition PHASE3 This study will enroll participants aged 12 years or older with a body weig...
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Active Not Recruiting
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West China Hospital, Sichuan University
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A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis PHASE3 The primary objective is to evaluate the efficacy of CCX168 (avacopan) to i...
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Clinical Trial Site
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PS-002 for the Treatment of IgA Nephropathy in Adults PHASE1 The purpose of the study is to evaluate safety, tolerability, and prelimina...
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University of Miami Hospital
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Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema PHASE2 It is a placebo-controlled randomized trial to evaluate the efficacy and sa...
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National Research Center - Institute of Immunology Federal Medical-Biological Agency of Russia
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Clinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated Vasculitis PHASE2 The aim of this trial is to test the safety and efficacy of two dose regime...
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Multiple Locations
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Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat Glomerulonephritis PHASE2 The purpose of this study is to evaluate the efficacy, safety, pharmacokine...
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Multiple Locations
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Radiotherapy Dose Complement in the Treatment of Hypoxic Lesions Patients With Stage III Non-small-cell Lung Cancer PHASE2 This study will assess the efficacy and safety of a radiotherapy dose compl...
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Centre Henri Becquerel
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Study of ARO-C3 in Adult Healthy Volunteers and Patients With Complement Mediated Renal Disease PHASE1 The purpose of AROC3-1001 is to evaluate the safety, tolerability, pharmaco...
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Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN) PHASE2 The objectives of this study are to evaluate the safety and efficacy of rav...
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